{"id":605,"date":"2026-10-02T21:01:51","date_gmt":"2026-10-02T19:01:51","guid":{"rendered":"https:\/\/investigaciondelcancerengalicia.gal\/?p=605"},"modified":"2026-10-05T10:47:19","modified_gmt":"2026-10-05T08:47:19","slug":"novas-estratexias-para-a-inmunoterapia-celular-do-cancro-de-pulmon","status":"publish","type":"post","link":"https:\/\/investigaciondelcancerengalicia.gal\/gl\/oncologia\/nuevas-estrategias-inmunoterapia-celular-cancer-pulmon\/","title":{"rendered":"Novas estratexias na inmunoterapia celular est\u00e1n a revolucionar o tratamento do cancro de pulm\u00f3n"},"content":{"rendered":"<p class=\"wp-block-paragraph\"><strong>Unha revisi\u00f3n publicada en *Frontiers in Immunology* examina o estado actual das terapias celulares que redirixen os linfocitos T contra o cancro de pulm\u00f3n. Algunhas xa est\u00e1n a mostrar beneficios significativos, mentres que outras permanecen nas fases iniciais do desenvolvemento.<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">O estudo, levado a cabo por un equipo liderado por Zhao e os seus colegas, ofrece unha revisi\u00f3n detallada das diversas estratexias de inmunoterapia celular que se est\u00e1n a investigar actualmente para o cancro de pulm\u00f3n e dos seus resultados ata a data.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Tarlatamab: mellora da supervivencia global<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Entre as terapias analizadas, tarlatamab destaca como o \u00fanico tratamento con aprobaci\u00f3n tradicional da FDA para esta enfermidade. No estudo DeLLphi-304, demostrou unha mellora significativa na supervivencia global: 13,6 meses fronte a 8,3 meses.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Linfocitos infiltrantes o tumor combinados con pembrolizumab<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">A infusi\u00f3n de linfocitos infiltrantes de tumor (TILs), combinada con pembrolizumab, presenta a maior taxa de resposta obxectiva en pacientes con cancro de pulm\u00f3n de c\u00e9lulas non pequenas (NSCLC) que non foron tratados previamente con inhibidores dos puntos de control inmunitario: 64.3%.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">CAR-T e TCR-T, a\u00ednda nas fases iniciais<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">As terapias CAR-T e TCR-T a\u00ednda est\u00e1n nas fases iniciais de desenvolvemento neste contexto, con taxas de resposta de menos do 10% nestes pacientes.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">A pesar dos avances realizados, os autores sinalan que a\u00ednda quedan numerosos desaf\u00edos na aplicaci\u00f3n de terapias celulares ao tratamento do cancro de pulm\u00f3n. Os resultados var\u00edan moito entre diferentes estratexias, e moitas delas a\u00ednda est\u00e1n na fase de investigaci\u00f3n.<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Font orixinal:<\/strong> <a href=\"https:\/\/biodigitalhealth.com\/medical_news\/81\/\" target=\"_blank\" rel=\"noreferrer noopener\">\u00abNovas estratexias na inmunoterapia celular est\u00e1n a revolucionar o tratamento do cancro de pulm\u00f3n\u00bb, Biodigital Health (7 de setembro de 2026)<\/a>.<\/p>","protected":false},"excerpt":{"rendered":"<p>Unha an\u00e1lise publicada en *Frontiers in Immunology* analiza as terapias que redirixen os linfocitos T no cancro de pulm\u00f3n: o tarlatamab mellora a supervivencia global, As TILs combinadas con pembrolizumab acadan unha taxa de resposta do 64,3%, mentres que as terapias CAR-T e TCR-T permanecen en ensaios en fases iniciais.<\/p>","protected":false},"author":3,"featured_media":623,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[24],"tags":[],"class_list":["post-605","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-oncologia"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.7 - 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